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Gabapentin Absorption

Horizant® exposure was shown to increase in proportion with the dose2

  • Because Horizant® is absorbed differently, plasma concentration increases predictably as the dose increases2

AUC=area under the curve.

Horizant® is not interchangeable with other gabapentin products.1

The clinical significance of the PK data for Horizant® and gabapentin is unknown.

Dose proportionality of Horizant® vs gabapentin AUC in blood after single oral doses2

Gabapentin Absorption

Adapted from Cundy KC et al. J Clin Pharmacol. 2008;48(12):1383.