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Horizant® Absorption
High-capacity transporters absorb Horizant® throughout the intestinal tract2 
Extended gabapentin exposure for up to 8.4 hours2
- Conventional gabapentin absorption pathway may become saturated, limiting the amount of drug that reaches systemic circulation2
- Horizant® is a PROdrug recognized by high-capacity nutrient transporters located through the intestinal tract2
- Horizant®’s absorption pathway does not become saturated at clinically relevant doses, enabling a greater proportion of the dose of drug to reach systemic circulation2
Horizant® is not interchangeable with other gabapentin products.1
The clinical significance of the PK data for Horizant® and gabapentin is unknown.
Absorption with Horizant®7

Adapted from Lal R et al. Ther Drug Monit. 2022;44(3):449.