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Horizant® Absorption

High-capacity transporters absorb Horizant® throughout the intestinal tract2

Extended gabapentin exposure for up to 8.4 hours2

  • Conventional gabapentin absorption pathway may become saturated, limiting the amount of drug that reaches systemic circulation2
  • Horizant® is a PROdrug recognized by high-capacity nutrient transporters located through the intestinal tract2
  • Horizant®’s absorption pathway does not become saturated at clinically relevant doses, enabling a greater proportion of the dose of drug to reach systemic circulation2

Horizant® is not interchangeable with other gabapentin products.1

The clinical significance of the PK data for Horizant® and gabapentin is unknown.

Absorption with Horizant®7

Absorption

Adapted from Lal R et al. Ther Drug Monit. 2022;44(3):449.