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PharmacokineticsRLSRLS GuidelinesPHNDosingSavingsSummary

AASM Clinical Practice Guidelines now suggest AGAINST the standard use of dopamine agonists (DAs)a

aDAs may be used to treat RLS by patients who place a higher value on the reduction of restless legs symptoms in the short term and a lower value on adverse effects (particularly augmentation with long-term use).

AASM=American Academy of Sleep Medicine.

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Updates

RLS Guideline Updates5

The long-term risk of augmentation with DA use is now clearer, which led to the conditional recommendation against the standard use of

  • Levodopa
  • Pramipexole
  • Rotigotine Transdermal Patch
  • Ropinirole